Targeted immunomodulators are a group of drugs used in dermatology to treat a variety of inflammatory skin conditions. They work by targeting specific components of the immune system, such as cytokines, receptors, or enzymes, which play a role in the development of inflammation. Some of the commonly used targeted immunomodulators in dermatology include biologic agents, such as TNF-alpha inhibitors, IL-17 inhibitors, and IL-23 inhibitors.

In this module, you will learn about the different types of targeted immune modulators available, their mechanisms of action, indications, contraindications, side effects effects, and more.

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Sources

  1. Comprehensive Dermatological Drug Therapy in Dermatology, 4th edition, Stephen Wolverton

  2. Psoriasis which therapy for which patient, Kaushik and Lebwohl, JAAD CME January 2019

  3. Dermatology, 4th edition, Jean L Bolognia

  4. Long term efficacy of Biologics in Dermatology, Dermatol Ther 2010, Voorhees

  5. Fitzpatricks Dermatology, 9th edition, Sewan kang et al.

  • Release Date: June 21, 2023

  • Last Updated: June 21, 2023

  • Time to complete: 30 minutes

  • Authors:

    • Dr. Zeinah Alhalees, MD, University of British Columbia.
    • Dr. Naif Aljahani, MD, Prince Sultan Military Medical City.
    • Dr. Rahul Nanda, MD, McGill University.
    • Dr. Elena Netchiporouk, MD, McGill University