Systemic sclerosis, also known as scleroderma, is a chronic autoimmune disease characterized by abnormal growth of connective tissue throughout the body. It affects the skin, blood vessels, and internal organs, leading to fibrosis (thickening and hardening) and vascular abnormalities. The condition can vary in severity and may affect different organs, such as the skin, lungs, heart, gastrointestinal tract, and kidneys.

This vignette is an excellent resource for residents preparing for OSCE-style examinations and can also be used as a self-directed learning tool for healthcare professionals seeking to enhance their knowledge and skills in managing systemic sclerosis.

We invite you to explore the associated learning module and quizzes to reinforce your knowledge and test your understanding of this important topic.

1. Bolognia J, Schaffer JV, Cerroni L. Dermatology. 4th edition ed: Philadelphia, Pa.: Elsevier; 2018 9th November 2017. 2880 p.
2. Photo courtesy of DermNet NZ.