Pustular psoriasis is a rare and severe form of psoriasis characterized by the presence of sterile pustules on an erythematous base. It can be localized or generalized and may present as a life-threatening condition in its generalized form. This clinical vignette on pustular psoriasis aims to assist residents in recognizing and diagnosing this challenging condition. Through this case, users will learn about the clinical features of pustular psoriasis, its differential diagnosis, and appropriate diagnostic and management strategies.

This vignette is an excellent resource for residents preparing for OSCE-style examinations and can also be used as a self-directed learning tool for healthcare professionals seeking to enhance their knowledge and skills in managing pustular psoriasis.

We invite you to explore the associated learning module and quizzes to reinforce your knowledge and test your understanding of this important topic.

1. Bolognia, J., Schaffer, J. V., & Cerroni, L. (2018). Dermatology (4th ed.). Philadelphia, PA: Elsevier
2. Wolverton, S. E., & Wu, J. J. (2021). Comprehensive dermatologic drug therapy. Elsevier.
3. Photo credit: DermNet NZ, “Generalised Pustular Psoriasis”. https://dermnetnz.org/topics/generalised-pustular-psoriasis