Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous skin disorder of unknown etiology. It is characterized by the presence of follicular keratotic papules, scaling, and erythema, often with palmoplantar keratoderma. This clinical vignette on PRP aims to assist residents in recognizing and diagnosing this rare condition. Through this case, users will learn about the clinical features of PRP, its differential diagnosis, and appropriate diagnostic and management strategies.

This vignette is an excellent resource for residents preparing for OSCE-style examinations and can also be used as a self-directed learning tool for healthcare professionals seeking to enhance their knowledge and skills in managing PRP.

We invite you to explore the associated learning module and quizzes to reinforce your knowledge and test your understanding of this important topic.

Sources

  1. Bolognia J, Schaffer JV, Cerroni L. Dermatology. 4th edition ed: Philadelphia, Pa.: Elsevier; 2018 9th November 2017. 2880 p.
  2. De Rosa A, Gambardella A, Licata G, Alfano R, Argenziano G. Successful treatment of Pityriasis rubra pilaris with brodalumab. Australas J Dermatol. 2020;61(2):e249-e251. doi:10.1111/ajd.13215
  3. Engelmann C, Elsner P, Miguel D. Treatment of pityriasis rubra pilaris type i: a systematic review. European journal of dermatology. 2020;29(5):524-537. doi:10.1684/ejd.2019.3641
  4. Pilz AC, Seiringer P, Biedermann T, Eyerich K. Treatment of Pityriasis Rubra Pilaris With Guselkumab. JAMA Dermatol. 2019;155(12):1424–1426. doi:10.1001/jamadermatol.2019.2774

  • Release Date: April 18th 2023

  • Last Updated: April 18th 2023

  • Time to complete: 30 minutes

  • Authors:

    • Dr. Zeinah Alhalees, MD, University of British Columbia.
    • Dr. Mathieu Powell, MD, McGill University.
    • Dr. Elena Netchiporouk, MD, McGill University