Palmoplantar keratoderma (PPK) is a group of inherited skin disorders characterized by thickening of the skin on the palms of the hands and the soles of the feet. It is a type of keratoderma that specifically affects these areas. The condition typically presents as thickened, dry, and calloused skin on the palms and soles, which may appear yellowish or brownish in color. The affected skin can be rough, cracked, and may cause discomfort or pain. In some cases, PPK may be associated with additional symptoms such as blistering, redness, or scaling.
This quiz is designed to test your knowledge on the epidemiology, pathogenesis, clinical features, differential diagnosis and management of PPK. We encourage you to review the associated learning module before taking the quiz.
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Sources
- Bolognia, J., Cerroni, L., & Schaffer, J. V. (2018). Dermatology. Philadelphia: Elsevier.
- Wolverton, S. E. (2013). Comprehensive dermatologic drug therapy. Edinburgh: Saunders.

Release Date: June 26, 2023
Last Updated: June 26, 2023
Time to complete: 30 minutes
Authors:
- Dr. Alireza Faghihi Kashani, MD, CISSS-AT
- Dr. Elena Netchiporouk, MD, McGill University