Mycophenolic acid (MPA) is an immunosuppressive agent used in the management of various autoimmune and inflammatory dermatological conditions. This medication inhibits the proliferation of T and B cells, thereby reducing inflammation and preventing autoantibody formation. MPA is commonly used in the treatment of dermatomyositis, lupus erythematosus, and pemphigus vulgaris. It is also used as a steroid-sparing agent in the management of refractory autoimmune blistering diseases.

MPA is available in both oral and intravenous formulations. Common side effects include gastrointestinal symptoms, bone marrow suppression, and increased risk of infections. The use of MPA requires careful monitoring of blood counts and renal function. In dermatology, MPA is often used as a second-line agent for moderate to severe cases of autoimmune or inflammatory skin diseases that do not respond to conventional therapies.

This quiz is designed to test your knowledge of the pharmacology, mechanisms of action, indications, dosing, adverse effects, drug interactions, and monitoring requirements of mycophenolate acid in the treatment of pruritic dermatoses.

Successful completion of this quiz requires a good understanding of the clinical applications of mycophenolate acid as an immunosuppressive medication. We encourage you to review the associated learning module before taking the quiz.

Click on “Mark Quiz Complete” once completed to keep track of your learning in your dashboard.

Sources

  1. Bolognia JL: Dermatology, 4th ed; 2018.
  2. Stephen E Wolverton JJW: Comprehensive Dermatologic Drug Therapy 4th edn: Elsevier; 2020
  • Release Date: March 31 2023

  • Last Updated: March 31 2023

  • Time to complete: 30 minutes

  • Authors:

    • Dr. Zeinah Alhalees, MD, University of British Columbia.
    • Dr. Naif Aljahani, MD, Prince Sultan Military Medical City.
    • Dr. Elena Netchiporouk, MD, McGill University.