Melanoma, which is the most severe type of skin cancer, is prevalent in North America and ranks fifth among both men and women in the United States. Its incidence increases with age, and early detection is critical for improving patient outcomes and saving lives. While most patients detect melanomas themselves, physician detection is linked to more manageable tumors with better survival rates. Patients with thin, invasive melanoma can expect a prolonged disease-free survival and likely cure with proper treatment. In this learning module, you will find a key point review on melanoma focused on epidemiology, pathogenesis, clinical features, differential diagnosis and management.
To test your knowledge, we refer you to the associated Quiz (short answer format questions) and clinical vignettes simulating OSCE examinations. We hope you find this module useful and if you choose to submit new questions or vignettes to increase the content of this module or post comments on how we can improve this module for your learning, we look forward to them.
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Sources
- Bolognia JL, Schaffer JV, Cerroni L. Dermatology. Elsevier; 2018.
- Gardner LJ, Strunck JL, Wu YP, Grossman D. Current controversies in early-stage melanoma: Questions on incidence, screening, and histologic regression. Journal of the American Academy of Dermatology. 2019 Jan 1;80(1):1-2.
- Klapperich ME, Bowen GM, Grossman D. Current controversies in early-stage melanoma: Questions on management and surveillance. Journal of the American Academy of Dermatology.
2019 Jan 1;80(1):15-25. - American Cancer Society [Internet]; c2022. Key Statistics for Melanoma Skin Cancer; 2022 Jan 12. [Cited 2022 Feb 2]. American Cancer Society, Inc. Available from: https://www.cancer.org/cancer/melanoma-skin-cancer/about/key-statistics.html.

Release Date: April 23, 2022
Last Updated: January 26, 2023
Time to complete: 30 minutes
Authors:
- Dr. Lydia Ouchene, MD, McGill University
- Dr. Zeinah Alhalees, MD, University of British Columbia
- Dr. Elena Netchiporouk, MD, McGill University
- Dr. Elizabeth O’Brien, MD, McGill University

