Lupus erythematosus (LE) is separated into the systemic (SLE) and the cutaneous (CLE) forms of the disease. Patients with SLE experience constitutional symptoms such as fatigue, fever, and weight loss. They can be identified using either the ACR or SLICC criteria. Cutaneous LE presents with non-specific cutaneous lesions such as diffuse non-scarring alopecia, Raynaud phenomenon, nail fold telangiectasias and erythema, palmar erythema, papular and nodular mucinosis, vasculitis, Sweet-syndrome-like neutrophilic dermatosis, and cutaneous signs of APS.

In this learning module, you will find a key point review on LE focused on epidemiology, pathogenesis, clinical features, differential diagnosis and management. To test your knowledge, we refer you to the associated Quiz (short answer format questions) and clinical vignettes simulating OSCE examinations. We hope you find this module useful and if you choose to submit new questions or vignettes to increase the content of this module or post comments on how we can improve this module for your learning, we look forward to them.

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1. Bolognia JL, Schaffer JV, Cerroni L. Dermatology. Elsevier; 2018.