Lichen planus is characterized by small, pruritic, polygonal, violaceous, flat-topped papules with or without umbilication, coalescence, Wickham striae, and Koebnerization on the flexor wrists, forearms, dorsal hands, shins, and presacrum. It is a rare disorder triggered by infection, vaccines, stress, contact allergens, or drugs in genetically predisposed individuals. It occurs in 0.2% to 1% of the population, with the highest incidence in people between the ages of 30 and 60. This condition can affect various parts of the body including the skin, oral cavity (75% of patients), scalp, nails, genitalia, and esophagus. Lichen striatus, lichen nitidus, erythema dyschromicum perstans, keratosis lichenoides chronica, actinic lichen nitidus, and annular lichenoid dermatitis (of youth) will also be tested in this section.
This quiz is designed to test your knowledge on the epidemiology, pathogenesis, clinical features, differential diagnosis and management of lichen planus and lichen dermatoses. We encourage you to review the associated learning module before taking the quiz.
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Sources
- Bolognia, J., Cerroni, L., & Schaffer, J. V. (2018). Dermatology.
- Tziotzios, Christos, John Y.w. Lee, Timothy Brier, Ryo Saito, Chao-Kai Hsu, Kapil Bhargava, Catherine M. Stefanato, David A. Fenton, and John A. McGrath. “Lichen Planus and Lichenoid Dermatoses: Clinical Overview and Molecular Basis.” Journal of the American Academy of Dermatology, vol. 79, no. 5 (November 2018): 789-804. https://doi.org/10.1016/j.jaad.2018.02.010.
- Tziotzios, Christos, John Y.w. Lee, Timothy Brier, Ryo Saito, Chao-Kai Hsu, Kapil Bhargava, Catherine M. Stefanato, David A. Fenton, and John A. McGrath. “Lichen Planus and Lichenoid Dermatoses: Conventional and Emerging Therapeutic Strategies.” Journal of the American Academy of Dermatology, vol. 79, no. 5 (November 2018): 807-818. https://doi.org/10.1016/j.jaad.2018.02.0103.
- Lavanya, N., Jayanthi, P., Rao, U. K., & Ranganathan, K. (2011). Oral lichen planus: An update on pathogenesis and treatment. Journal of oral and maxillofacial pathology : JOMFP, 15(2), 127–132. https://doi.org/10.4103/0973-029X.84474
- Weston, G., & Payette, M. (2015). Update on lichen planus and its clinical variants. International journal of women’s dermatology, 1(3), 140–149. https://doi.org/10.1016/j.ijwd.2015.04.001

Release Date: March 4, 2023
Last Updated: March 4, 2023
Time to complete: 45 minutes
Authors:
- Dr. Kathleen D’Aguanno, MD, Sherbrooke University
- Dr. Elena Netchiporouk, MD, McGill University

