Keratolytics are a group of agents that are used in dermatology for the treatment of various skin conditions that involve hyperkeratosis or thickened skin. These agents work by breaking down the keratin protein that forms the outermost layer of the skin, thereby promoting the shedding of dead skin cells and the subsequent smoothing of the skin surface.

Keratolytics can be used to treat a variety of conditions, such as psoriasis, corns, calluses, and acne. The different types of keratolytics include alpha-hydroxy acids, beta-hydroxy acids, urea, and salicylic acid. They are available in various formulations, including creams, lotions, gels, and solutions, and the concentration of the active ingredient may vary depending on the intended use and severity of the condition. Common adverse effects of keratolytics include skin irritation, dryness, and peeling.

This quiz is designed to test your knowledge on keratolytics, including their mechanisms of action, indications, contraindications, adverse effects, and drug interactions.

Successful completion of this quiz requires a good understanding of the different types of keratolytics and their clinical applications. We encourage you to review the associated learning module before taking the quiz.

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1. Bolognia JL: Dermatology, 4th ed; 2018.
2. Stephen E Wolverton JJW: Comprehensive Dermatologic Drug Therapy 4th edn: Elsevier; 2020