Human papillomavirus (HPV) is a species-specific non-enveloped double stranded DNA virus resistant to heat and desiccation which may cause cervical cancer, anal cancer, cutaneous warts, mucosal warts, genital condylomata, and recurrent respiratory papillomatosis. The replication of HPV is linked to epithelial differentiation. Most HPV infections typically resolve within 12 months, while persistent infections increase the risk of precancerous or cancerous lesions. Different HPV types have a propensity to infect different body sites and are associated with various diseases. Different types of HPV are associated to specific cutaneous and mucosal manifestations and certain types have a known association to squamous cell carcinoma and Bowen’s disease, with HPV 16 being the most common one.

This quiz is designed to test your knowledge on the epidemiology, pathogenesis, clinical features, differential diagnosis and management of conditions associated with HPV. We encourage you to review the associated learning module before taking the quiz.

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• Bolognia, J., Cerroni, L., & Schaffer, J. V. (2018). Dermatology.