ExtraMammary Paget’s Disease (EMPD) is a rare, slow-growing intraepithelial malignancy, primarily affecting the apocrine gland-rich areas such as the vulva, perianal region, and axilla. It presents as a persistent, pruritic, eczematous or erythematous patch or plaque, often with scaling and crusting. This clinical vignette on EMPD aims to guide residents in recognizing and diagnosing this rare condition. Through this case, users will learn about the clinical features of EMPD, its differential diagnosis, and appropriate diagnostic and management strategies.

This vignette is an excellent resource for residents preparing for OSCE-style examinations and can also be used as a self-directed learning tool for healthcare professionals seeking to enhance their knowledge and skills in managing EMPD.

We invite you to explore the associated learning module and quizzes to reinforce your knowledge and test your understanding of this important topic.

1. Bolognia, J., Schaffer, J. V., & Cerroni, L. (2018). Dermatology (4th ed.). Philadelphia, PA: Elsevier.
2. Photo courtesy: DermNet NZ, Dermnetnz.org “extramammary Paget’s disease”
3. McDaniel B, Brown F, Crane JS. Extramammary Paget Disease. [Updated 2022 Aug 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK493224/