Return to course: Agents used for the Treatment of Pruritus
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Doxepin
Cat. B
Lactation: not recommended
Preparations
5% cream (QID up to 7 days)
Mechanism of Action
TCA & antihistamine (H1 & H2)
Indications
Atopic dermatitis
Nummular eczema
Lichen simplex chronicus
CI
Untreated Narrow angle glaucoma
Urinary retention
MAOI
Side Effects
Drowsiness & sedation
ICD
ACD
Systemic contact dermatitis (rare)
Other
Drowsiness secondary to systemic absorption seen in a quarter of patients using topical Doxepin