Marginal Papular Keratoderma: Acrokeratoelastoidosis and Focal Acral Hyperkeratosis

  • Autosomal dominant inheritance
  • Childhood / adolescence onset
  • Focal acral hyperkeratosis more typical among females, especially of African lineage

  • Unknown

  • Small, palmoplantar and digital (borders) keratotic papules with potential for umbilication
    • Hyperpigmented / skin coloured in focal acral hyperkeratosis
    • Yellow coloured in acrokeratoelastoidosis
  • Possible marginal keratoderma variant with polygonal papules among African patients, with shin, ankles, dorsal hands / feet involvement
  • Keratoelastoidosis marginalis is an acquired digital papular calcific elastosis with severe photodamage

Pathology acrokeratoelastoidosis:

  • Elastorrhexis

  • Unknown