Diffuse Palmoplantar Keratodermas (Isolated, Non-Syndromic)
Diffuse Palmoplantar Keratodermas with Ichthyosis
Diffuse Palmoplantar Keratodermas with Associated Features/Syndromic
Focal Palmoplantar Keraoderma without Associated Features
Focal Palmoplantar Keraoderma with Associated Features/Syndromic
Punctate Palmoplantar Keratoderma without Associated Features
Punctate Palmoplantar Keratoderma with Associated Features Syndromic
Acquired Keratodermas and Related Conditions
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Cole Disease
- Rare
- Ectonucleotide pyrophosphatase / phosphodiesterase 1 gene mutations
- Autosomal recessive inheritance
- Altered hydrolysis of adenosine triphosphate to adenosine monophosphate
- Uninhibited mineralization with potential for ectopic calcification
- Punctate palmoplantar keratoderma, irregular hypopigmented macules of extremities appearing in childhood or at birth
- Possible calcific tendinopathy and calcinosis cutis
- Unknown
- Unknown