Focal Palmoplantar Keraoderma without Associated Features
Striate / Focal Palmoplantar Keratoderma
Punctate Palmoplantar Keratoderma with Associated Features Syndromic
Cole Disease
Take the Clinical Vignette
Clinical Vignette

Overview

  • Vörner–Unna–Thost: epidermolytic
  • Nagashima, Kimonis: non-epidermolytic 
  • Bothnia: non-epidermolytic
  • Greither: transgrediens and progrediens
  • Mal de Meleda: non-epidermolytic

  • Vohwinkel syndrome
  • Bart–Pumphrey syndrome
  • Palmoplantar keratoderma due to connexin 26 defect
  • Mitochondrial palmoplantar keratoderma
  • Huriez syndrome
  • Palmoplantar keratoderma with sex reversal
  • Clouston syndrome
  • Odonto-onycho-dermal dysplasia
  • Schöpf–Schulz–Passarge syndrome
  • Keratoderma–hypotrichosis–leukonychia totalis
  • Olmsted syndrome
  • Papillon–Lefèvre syndrome 
  • Loricrin keratoderma
  • Keratosis linearis, ichthyosis congenita, sclerosing keratoderma
  • Naxos disease

  • Brünauer–Fuhs–Siemens
  • Wachters

  • Pachyonychia congenita
  • Focal palmoplantar and gingival keratosis: epidermolytic
  • Howel–Evans syndrome
  • Richner–Hanhart syndrome (oculocutaneous tyrosinemia) 
  • Carvajal syndrome
  • Palmoplantar keratoderma and woolly hair

  • Buschke–Fischer–Brauer
  • Spiny keratoderma
  • Marginal papular keratoderma
  • Punctate keratoses of the palmar creases
  • Porokeratosis punctata palmaris et plantaris

  • Cole disease
  • Peeling skin, leukonychia, cheilitis, knuckle pads syndrome

  • Keratoderma climactericum 
  • Aquagenic palmoplantar keratoderma 
  • Pityriasis rubra pilaris 
  • Associated with hypothyroidism / myxedema 
  • Associated with cancer
  • Associated with lymphedema 
  • Associated with dermatomyositis
  • Arsenical keratoses 
  • Drug-induced keratoderma 
  • Induced by dioxin or halogenated herbicides

Hereditary Disorders

  • Basal cell nevus syndrome
  • Basaloid follicular hamartoma syndrome 
  • Darier disease 
  • Reticulate acropigmentation of Kitamura 
  • Punctate palmoplantar keratoderma
  • Cowden syndrome
  • Porokeratotic adnexal ostial nevus

Acquired Disorders

  • Pitted keratolysis 
  • Associated with Dupuytren contracture 
  • Punctate porokeratoses