Lichen striatus

  • Uncommon 
  • Children and young adults 
  • Females > Males if generalized 
  • Associated with Down syndrome, Crohn’s, atopic dermatitis and congenital megacolon 
  • Familial form (rare)

  • Unknown etiology
  • Thought to be a different manifestation to similar triggering factors as lichen planus (for example hepatitis B vaccine)

  • Multiple, tiny, discrete, shiny, skin-colored, uniform, pinhead-sized papules ± umbilication, pruritus, Koebner
  • Cluster in flexor areas of upper extremities, chest, abdomen, dorsal hands, genitalia >> face, neck, lower extremities, palms, soles, mucous membranes
  • Chronic eruption (<1 year) 
  • Rare oral involvement: 
    • Soft mucosa: tiny, flat, gray-white papules 
    • Hard palate/tongue: white plaques
  • Nail involvement:
    • 10% patients (usually adults)
    • Pitting, rippling, longitudinal ridging, terminal splitting, longitudinal linear striations 
  • Variants: 
    • Vesicular and hemorrhagic
    • Palmoplantar
    • Linear
    • Follicular spines
    • Perforating (associated with lichen planus)
    • Generalized (lesions coalesce)
    • Actinic (young adults, fitz 4-5)

  • Infiltrate of lymphocytes, epithelioid cells ± Langerhans cells, confined between 2-3 dermal papillae 🡪 “ball and claw”
  • Overlying atrophic epidermis and thin/absent granular layer
  • Central parakeratotic cap 
  • Vacuolar degeneration ± Max Joseph spaces and colloid bodies 
  • Melanin incontinence

  • Lichen planus
  • Guttate lichen sclerosus 
  • Lichen spinulosus 
  • Frictional lichenoid dermatitis (elbows and knees)
  • Papular eczema 
  • Verruca plana
  • Lichen scrofulosorum 
  • Lichen striatus 
  • Papular sarcoidosis 
  • Lichenoid variant of secondary syphilis

  • Spontaneously resolves within 1 year
  • Pruritus: topical corticosteroids and oral antihistamines 
  • Children: topical calcineurin inhibitors 
  • Generalized disease unresponsive to topical treatment: Narrowband ultraviolet B/Psoralen and ultraviolet A