Clinical

• Targeted history (type of irritant, timing, dose, presence of risk factors) 
• Clinical characteristics can overlap with ACD but usually more limited to area exposed and burning ± pruritic

Pathology

• Varies from mild spongiosis to necrosis of epidermal keratinocytes, inflammatory infiltrate
• Most typical: neutrophil-rich superficial perivascular infiltrate with widely scattered necrotic keratinocyte
• Increasing chronicity: acanthosis, mild hypergranulosis, hyperkeratosis 

Further investigations: detailed history of work, habits, hobbies; Patch testing if warranted