Systemic Antifungals
Topic Antifungals
Quiz
Resources
Polyenes
Nystatin
- Pregnancy Category B
- 100000 USP units/g
- Cream, ointment, powder
- Oral suspension: 2-5 times a day
- Slow Dissolving Pastille (lozenge): 4-5 times a day
- Fungistatic & fungicidal
- Binds to membrane sterols of susceptible Candida species, increases membrane permeability leading to leakage of essential intracytoplasmic components
- Candida albicans & other Candida spp.
- Ineffective against Dermatophytes
- Burning, pruritis, rash, eczema, pain on application
- Rarely hypersensitivity reactions
- Insoluble in water, is not absorbed from intact skin, gastrointestinal tract or vagina