Urticaria Pigmentosa – low magnification
LEGEND
Sometimes, hyperpigmentation of the basement membrane and a few melanophages in the superficial dermis are observed.
Note: The histopathological changes of mastocytosis are often very subtle, and the specimen may resemble normal skin.
Superficial perivascular infiltrate of mast cells +/- eosinophils
Urticaria Pigmentosa – high magnification
LEGEND
Mast cells have a large central nucleus with a “fried egg” appearance. They contain granules.
Urticaria Pigmentosa
LEGEND
Superficial perivascular infiltrate of mast cells +/- eosinophils
Sometimes, hyperpigmentation of the basement membrane and a few melanophages in the superficial dermis are observed.
Mast cells have a large central nucleus with a “fried egg” appearance. They contain granules.
