Invasive acral lentiginous melanoma – low magnification

LEGEND

Presence of superficial ulceration

  • Dense proliferation of atypical spindle-shaped melanocytes in the dermis

  • Reactive infiltrate of inflammatory cells at the periphery

Invasive acral lentiginous melanoma – high magnification

LEGEND

  • Presence of undifferentiated atypical spindle cells

    Variable size.

Invasive acral lentiginous melanoma

Melan-A positive

Invasive acral lentiginous melanoma

S100 positive

Invasive acral lentiginous melanoma

SOX-10 positive