Desmoplastic melanoma – low magnification
LEGEND
The majority of cases also have an intraepidermal component of the lentiginous or superficial spreading type.
Occasional solar elastosis
This type of melanoma is often locally aggressive.
Melan-A and HMB-45 are typically negative, and SOX-10 is positive
Proliferation of spindle-shaped melanocytes, with or without atypia, in the dermis forming bundles between collagen fibers
Presence of a desmoplastic stroma: meaning it is hypocellular and fibrotic
Desmoplastic melanoma – high magnification
Proliferation of spindle-shaped melanocytes forming bundles between collagen fibers
Presence of a desmoplastic stroma: meaning it is hypocellular and fibrotic
