Table of Contents
Dermatofibroma – low magnification
DF changes in the early days
Dermatofibroma
LEGEND
More or less well-demarcated nodule in the dermis that may extend into the hypodermis.
Composed of spindle-shaped or triangular fibroblasts
Presence of histiocytes
Multinucleated or foamy giant cells may be present
Peripheral clusters of dense collagen (keloidal collagen), often sequestered by fibroblasts
Flattening of epidermal ridges
- Presence of a Grenz zone
Dermatofibroma
LEGEND
A +/- well-defined nodule in the dermis that gradually fades at the periphery.
Dermatofibroma
LEGEND
Keloidal collagen surrounded by fibroblasts frequently found at the periphery of the lesion
Dermatofibroma
Dermatofibroma
LEGEND
Multinucleated giant cells
- Keloidal collagen
Spindle-shaped fibroblasts
- Triangular fibroblasts
Dermatofibroma
Storiform pattern may be present: bundles running in all directions, resembling a straw mat
