Table of Contents
Dermatofibrosarcoma protuberans
Proliferation of fibroblasts with storiform arrangement
Invasion of the hypodermis
Formation of a honeycomb pattern (also known as “honeycombing”)
Dermatofibrosarcoma protuberans
Invasion of the hypodermis
Formation of a honeycomb pattern
Dermatofibrosarcoma protuberans
Poorly demarcated tumor
Formation of a honeycomb pattern
Dermatofibrosarcoma protuberans
Storiform pattern: bundles oriented in all directions
Appearance similar to a straw mat
Dermatofibrosarcoma protuberans
LEGEND
Honeycomb pattern with fibroblasts invading and separating adipocytes
Dermatofibrosarcoma protuberans
Spindle-shaped fibroblasts with rare mitoses
CD34 positivity
Factor XIIIa negativity
Dermatofibrosarcoma protuberans
Rare mitoses
No atypia
Storiform pattern composed of spindle-shaped cells
