Macronodular basal cell carcinoma – low magnification
LEGEND
Epidermal tumor with connection to the epidermis
Islands of variable size composed of basaloid cells
Retraction clefts between tumor cells and adjacent stroma
Macronodular basal cell carcinoma
LEGEND
- Epidermal tumor with connection to the epidermis
Composed of basaloid cells (bluish, resembling basal layer cells) with varying degrees of cellular atypia
Palisading
Macronodular basal cell carcinoma
LEGEND
The mucinous stroma, cellular atypia, and retraction clefts are features that help differentiate basal cell carcinoma from trichoblastoma.
- Mucinous stroma (pale blue appearance between collagen fibers)
Macronodular basal cell carcinoma
LEGEND
- Islands of basaloid cells with palisading arrangement (resembling a fence)
- Lymphocytic infiltrate may be present
- Mucinous stroma
