Common wart

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Marked papillomatosis

  • Elongation of the epidermal rete ridges with invagination into the dermis, exhibiting a “crab claw” appearance.

Common wart

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Capped by pronounced hyperkeratosis.

  • Marked church spire papillomatosis also known as “church spire pattern”.

Common wart

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  • Church spire pattern papillomatosis

  • Compact hyperkeratosis

  • Focal hemorrhages

  • Parakeratotic mound

Common wart

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  • Parakeratotic mound (keratinocytes in the stratum corneum with preserved nuclei)

  • Focal hemorrhages

Common wart

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The presence of thrombosed capillaries in a wart explains the frequent clinical finding of small brownish petechiae within the lesion— a sign best observed after debridement of the hyperkeratosis.

  • Dilated capillaries in the papillary dermis

Common wart

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  • Hypergranulosis in the valleys

Common wart

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Presence of large keratohyalin granules

The presence of koilocytes is a characteristic finding of keratinocytes infected by human papillomavirus (HPV).

  • Koilocytes

    • Koilocytes located in the granular layer.

    • Defined by the presence of a perinuclear clear halo (360°) with a pyknotic nucleus and a slightly darker border around the nucleus center (representing eccentric chromatin).

Common wart

Koilocytes in the granular layer – high magnification