Atypical mycobacteria

LEGEND

  • Formation of suppurative granulomas in the dermis
  • Epidermal hyperplasia

Atypical mycobacteria

LEGEND

  • Pseudoepitheliomatous hyperplasia (reactive epidermal proliferation)
  • Suppurative granulomas

Atypical mycobacteria

LEGEND

  • Suppurative granulomas, defined as a collection of epithelioid histiocytes with formation of multinucleated giant cells and an abundant neutrophilic infiltrate

Atypical mycobacteria

LEGEND

  • Suppurative granulomas, defined as a collection of epithelioid histiocytes with formation of multinucleated giant cells and an abundant neutrophilic infiltrate

Atypical mycobacteria

LEGEND

  • Suppurative granulomas with dense neutrophilic infiltrate
  • Multinucleated giant cells

  • Mixed inflammatory infiltrate composed of polymorphonuclear cells, lymphocytes and histiocytes

  • Edematous stroma

Atypical mycobacteria

LEGEND

Langhans-type giant cells have traditionally been associated with mycobacterial infections, although they may be found in various granulomatous conditions

  • Multinucleated giant cells of Langhans type (characterized by an arc of peripheral nuclei, resembling a horseshoe)

Atypical mycobacteria

LEGEND

These cells are formed by the fusion of macrophages, a common finding in granulomatous entities

  • Multinucleated giant cells

Atypical mycobacteria

Edematous stroma