Juvenile Xanthogranuloma

LEGEND

Diffuse infiltrates composed of histiocytes, multinucleated giant cells, foamy histiocytes, and Touton giant cells.

The infiltrate may also contain lymphocytes and eosinophils, particularly if the juvenile xanthogranuloma (JXG) is recent or represents a young lesion.

  • Touton giant cells: Multinucleated giant cells with peripheral foamy cytoplasm and a central ring of nuclei.

  • Multinucleated giant cells

Juvenile Xanthogranuloma

LEGEND

  • Multinucleated giant cells

  • Touton giant cells

Juvenile Xanthogranuloma

LEGEND

  • Foamy macrophages: The cytoplasm appears paler due to its high content of lipid droplets.

  • Multinucleated giant cells

Juvenile Xanthogranuloma

LEGEND

  • Foamy histiocytes