Eruptive xanthoma

LEGEND

Lipid deposition in the dermis associated with a mixed inflammatory infiltrate.

  • The histologic hallmark of xanthomas is the presence of foamy cells, which are macrophages that have phagocytosed lipids.

Eruptive xanthoma

Immunohistochemistry for adipophilin is positive. It stains the cytoplasm of macrophages that contains lipids.