Leg-type diffuse large B-cell lymphoma – low magnification

LEGEND

The cells are positive for CD20, CD79, MUM-1, Bcl-2, Bcl-6. Negative for CD30.

  • Normal epidermis with a Grenz zone

  • Diffuse pan-dermal infiltrate of atypical lymphocytes

Leg-type diffuse large B-cell lymphoma – high magnification

LEGEND

  • Infiltrate is predominantly composed of centroblasts, which are large cells with a prominent nucleolus.

  • Minimal presence of centrocytes (cells of variable size, small to large, with an indented nucleus)