Kaposi sarcoma
Infiltrative tumor composed of spindle-shaped endothelial cells
Erythrocyte extravasation
Kaposi sarcoma
Infiltrative tumor composed of spindle-shaped endothelial cells
Erythrocyte extravasation
Kaposi sarcoma
Tumor composed of spindle-shaped endothelial cells dissecting collagen fibers (infiltrative nature)
Erythrocyte extravasation
Kaposi sarcoma
LEGEND
Erythrocyte extravasation
Tumor composed of spindle-shaped endothelial cells dissecting collagen fibers (infiltrative nature)
Kaposi sarcoma
LEGEND
Irregular crescent-shaped vascular slits (also known as slit-like vascular spaces) separating collagen fibers, mostly lined by a single layer of spindle-shaped endothelial cells
Marked extravasation
Kaposi sarcoma
LEGEND
Histopathological triad of Kaposi sarcoma = hemosiderin + plasma cells + hyaline globules
Hemosiderin granules indicative of erythrocyte extravasation
Kaposi sarcoma
LEGEND
Histopathological triad of Kaposi sarcoma = hemosiderin + plasma cells + hyaline globules
Hyaline globules
Kaposi sarcoma
LEGEND
Histopathological triad of Kaposi sarcoma = hemosiderin + plasma cells + hyaline globules
Presence of plasma cells
Kaposi sarcoma
LEGEND
Nuclear pleomorphism (nuclei of varying sizes)
Presence of mitoses
Kaposi sarcoma
LEGEND
Nuclear pleomorphism (nuclei of varying sizes)
Presence of mitoses
Kaposi sarcoma
LEGEND
Presence of plasma cells
Presence of hyaline globules
Tumor composed of spindle-shaped endothelial cells that dissect collagen fibers (infiltrative character)
- Erythrocytes etravasation and hemosiderin deposition in the dermis
Kaposi sarcoma – HHV8 positive
LEGEND
Immunohistochemistry detects the presence of HHV8 in the cells
