Post-radiation atypical vascular lesion

LEGEND

This is a tumor with clinical and histological overlap with well-differentiated angiosarcoma.

Vascular spaces of variable size lined by a single layer of endothelial cells

Proliferation dissecting collagen fibers

  • Differentiation from angiosarcoma is based on the fact that the atypical vascular lesion is less infiltrative, has a more superficial localization, and shows very few cellular atypia with low mitotic activity.

Post-radiation atypical vascular lesion

LEGEND

  • Proliferation of irregular and angulated vascular slits dissecting the collagen fibers of the papillary and reticular dermis

Post-radiation atypical vascular lesion

Anastomosis of irregular and angulated vascular slits

Post-radiation atypical vascular lesion

LEGEND

  • Vascular spaces of variable size lined by a single layer of endothelial cells