Porphyria cutanea tarda
LEGEND
Subepidermal blister with a viable roof and pauci-inflammatory pattern (very mild inflammation)
Hyaline deposits (pale pink and homogeneous) around blood vessels
Caterpillar bodies: characterized by eosinophilic material arranged in a linear pattern originating from the basement membrane. When located beneath the blister roof, it resembles a caterpillar
This finding is not specific to porphyria
Porphyria cutanea tarda
LEGEND
Very mild to absent inflammation
Hyaline deposits (pale pink and homogeneous) around blood vessels.
Dermal fibrosis with denser and more prominent collagen fibers.
Porphyria cutanea tarda
LEGEND
All characteristic features of porphyria are visible in this section
Subepidermal blister with a viable roof and mild inflammation
Hyaline deposits around blood vessels
Dermal fibrosis
Festooning: preservation of the shape of the dermal papillae
