Table of Contents

Pemphigus vulgaris – low magnification

Massive suprabasal acantholysis

Dermal papillae are preserved, with rupture of the bridges between keratinocytes in the basal layer, resembling intestinal villi or rows of tombstones

Very subtle dyskeratosis may be present

Mixed inflammatory infiltrate

Pemphigus vulgaris – suprabasal acantholysis

LEGEND

  • Dermal papillae are preserved, with rupture of the bridges between keratinocytes in the basal layer, resembling intestinal villi or rows of tombstones

    However, the basal keratinocytes remain attached to the basement membrane

Pemphigus vulgaris – inflammatory infiltrate

LEGEND

  • Eosinophils

  • Neutrophils

  • Lymphocytes