Morphea
LEGEND
Sclerosing inflammatory disorder of the dermis extending into the hypodermis
Atrophic epidermis
Hyalinization of the papillary and reticular dermis (becomes hyalinized, meaning pink and uniform)
Thickening of collagen fibers
Eccrine glands appear more superficially located in the dermis due to sclerosis extending into the hypodermis
Biopsy specimen appears square-shaped due to the abundance of thick and rigid collagen fibers (also known as squared-off edges)
Entrapment of eccrine glands by sclerotic and rigid collagen fibers
Morphea
LEGEND
Collagen fibers become sclerotic, thickened, and rigid
Entrapment of eccrine glands
Morphea
LEGEND
Collagen fibers become sclerotic, thickened, and rigid
Entrapment of eccrine glands
Morphea
LEGEND
Sclerosis of collagen fibers extending into the hypodermis, leading to thickening of fat lobule septa
Considered a form of septal panniculitis
Morphea
LEGEND
Superficial and deep perivascular infiltrate of lymphocytes and plasma cells
Perivascular collections of lymphocytes and plasma cells at the dermal-hypodermal junction
Morphea
LEGEND
As morphea plaques evolve, inflammation decreases, while sclerosis increases, potentially progressing to involve the hypodermis.
Plasma cells are present within the inflammatory infiltrate
