Linear IGA dermatosis – low magnification
LEGEND
Complete detachment between dermis and epidermis, creating a subepidermal blister
- Perivascular infiltrate of lymphocytes in superficial dermis
Linear IGA dermatosis – high magnification
LEGEND
Vacuolar changes are often seen in early stages
A linear deposition of IgA along the basement membrane is observed on direct immunofluorescence
The subepidermal blister is composed mainly of neutrophils with or without eosinophils
At the edges of the blister, neutrophils tend to cluster near the dermo-epidermal junction
