Pyoderma gangrenosum – low magnification

LEGEND

Altered epidermis: necrotic or ulcerated, sometimes pustular

Occasionally, pseudoepitheliomatous hyperplasia is seen at the edge of the ulcer

Secondary leukocytoclastic vasculitis may be present

  • Diffuse, dense and confluent neutrophil infiltrate in the dermis

Pyoderma gangrenosum – high magnification

LEGEND

  • Diffuse infiltrate of neutrophils and neutrophil debris in the dermis

  • Red blood cell extravasation