Neurofibroma


LEGEND
Well-defined tumor
Non-encapsulated tumor localized in the dermis
Neurofibroma – low magnification

Well-defined, non-encapsulated nodule that can extend into the hypodermis
Neurofibroma

Composed of spindle cells in a pale pink fibrillary stroma, often referred to as “bubble-gum” pink
Spindle cells with random arrangement
Neurofibroma

Well-defined tumor
Non-encapsulated tumor localized in the dermis
Stroma paler compared to the peripheral collagen
So-called “bubble-gum” stroma
Neurofibroma


LEGEND
Mainly composed of fibroblasts, Schwann cells, perineural cells, and mast cells (they may be present in variable quantities)
Spindle cells with wavy nuclei
Neurofibroma – fibrillary stroma










