Microcystic adnexal carcinoma – low magnification

Adnexal tumor with eccrine and follicular differentiation

Superficial and deep dermal tumor

Poorly circumscribed due to its infiltrative nature

Dense and sclerotic stroma extending deeply

Microcystic adnexal carcinoma

LEGEND

  • Tadpole-shaped sweat ducts composed of two layers of flattened cuboidal epithelial cells (similar to syringoma)

Microcystic adnexal carcinoma

Nests of basaloid cells characteristic of the follicular differentiation of this tumor

Microcystic adnexal carcinoma

LEGEND

  • Horn cysts characteristic of follicular differentiation

Microcystic adnexal carcinoma

LEGEND

  • Sweat ducts in infiltrative trabecular cords extending deeply (poorly circumscribed tumor)

  • Dense and sclerotic stroma

Microcystic adnexal carcinoma

LEGEND

  • Intracytoplasmic ductal lumen