Hidradenoma papilliferum – overview

Labyrinthine sweat gland structure without connection to the epidermis

Well-circumscribed

Commonly located in the vulvar and perineal regions

Hidradenoma papilliferum

LEGEND

Composed of both solid and cystic areas (the specimen shown here is predominantly cystic)

  • Fibrovascular stroma

    Unlike syringocystadenoma papilliferum, there are no inflammatory cells in the stroma (no lymphocytes or plasma cells)

Hidradenoma papilliferum

LEGEND

  • Apocrine decapitation secretion (also known as “apical snout”)

  • Two layers: a flattened/cuboidal basal layer and an overlying columnar layer