Hidradenoma papilliferum – overview

Labyrinthine sweat gland structure without connection to the epidermis
Well-circumscribed
Commonly located in the vulvar and perineal regions
Hidradenoma papilliferum


LEGEND
Composed of both solid and cystic areas (the specimen shown here is predominantly cystic)
Fibrovascular stroma
Unlike syringocystadenoma papilliferum, there are no inflammatory cells in the stroma (no lymphocytes or plasma cells)
Hidradenoma papilliferum


LEGEND
Apocrine decapitation secretion (also known as “apical snout”)
Two layers: a flattened/cuboidal basal layer and an overlying columnar layer

