Syringocystadenoma papilliferum

LEGEND

  • Adnexal tumor in connection with the epidermis

  • Papillary projections invaginating into cystic spaces

Syringocystadenoma papilliferum

LEGEND

  • Adnexal tumor connected to the epidermis

  • Villous projections surrounded by cystic spaces

Syringocystadenoma papilliferum

LEGEND

All surrounded by cystic spaces

  • Papillae lined by a double-layered columnar epithelium

  • Inner layer composed of small cells. Outer layer composed of large columnar cells with abundant cytoplasm.

  • Presence of dilated vessels within the papillae

  • The center of the papillae contains an infiltrate rich in plasma cells

Syringocystadenoma papilliferum

LEGEND

  • Papillae lined by a double-layered columnar epithelium

  • Inner layer composed of small cells. Outer layer of large columnar cells with abundant cytoplasm. (Cutting artifact may give the impression of more than 2 layers)

  • Presence of dilated vessels within the papillae

  • The center of the papillae contains an infiltrate rich in plasma cells

Syringocystadenoma papilliferum

LEGEND

  • Papillae lined by a double-layered columnar epithelium

  • Inner layer of small cells. Outer layer of large columnar cells with abundant cytoplasm

  • Presence of dilated vessels within the papillae

  • Plasma cell–rich infiltrate in the core of the papillae

Syringocystadenoma papilliferum

LEGEND

  • Papillae lined by a double-layered columnar epithelium

  • Center of the papillae filled with a plasma cell–rich infiltrate

Syringocystadenoma papilliferum

LEGEND

  • Papillae lined by a double-layered columnar epithelium

  • Abundance of plasma cells in the center of the papillae

Syringocystadenoma papilliferum

LEGEND

  • Apocrine secretion

    Decapitation/fragmentation of the apical pole

    The columnar cells of the outer layer exhibit a prominent apical pole, which detaches from the rest of the cell during secretion