Syringocystadenoma papilliferum
LEGEND
Adnexal tumor in connection with the epidermis
Papillary projections invaginating into cystic spaces
Syringocystadenoma papilliferum
LEGEND
Adnexal tumor connected to the epidermis
Villous projections surrounded by cystic spaces
Syringocystadenoma papilliferum
LEGEND
All surrounded by cystic spaces
Papillae lined by a double-layered columnar epithelium
Inner layer composed of small cells. Outer layer composed of large columnar cells with abundant cytoplasm.
Presence of dilated vessels within the papillae
The center of the papillae contains an infiltrate rich in plasma cells
Syringocystadenoma papilliferum
LEGEND
Papillae lined by a double-layered columnar epithelium
Inner layer composed of small cells. Outer layer of large columnar cells with abundant cytoplasm. (Cutting artifact may give the impression of more than 2 layers)
Presence of dilated vessels within the papillae
The center of the papillae contains an infiltrate rich in plasma cells
Syringocystadenoma papilliferum
LEGEND
Papillae lined by a double-layered columnar epithelium
Inner layer of small cells. Outer layer of large columnar cells with abundant cytoplasm
Presence of dilated vessels within the papillae
Plasma cell–rich infiltrate in the core of the papillae
Syringocystadenoma papilliferum
LEGEND
Papillae lined by a double-layered columnar epithelium
Center of the papillae filled with a plasma cell–rich infiltrate
Syringocystadenoma papilliferum
LEGEND
Papillae lined by a double-layered columnar epithelium
Abundance of plasma cells in the center of the papillae
Syringocystadenoma papilliferum
LEGEND
Apocrine secretion
Decapitation/fragmentation of the apical pole
The columnar cells of the outer layer exhibit a prominent apical pole, which detaches from the rest of the cell during secretion