Necrobiosis lipoidica


LEGEND
Palisading (elongated histiocytes with nuclei aligned parallel to one another) is oriented parallel to the epidermis.
The epidermis may be normal, atrophic, or ulcerated.
Extensive necrobiosis extending into the hypodermis, with palisading histiocytes forming layered arrangements between zones of necrobiosis, resembling the appearance of lasagna.
Necrobiosis lipoidica – palisade


LEGEND
Palisading histiocytes
Arrangement parallel to the epidermis and collagen fibers
Necrobiosis lipoidica


LEGEND
Necrobiosis located between palisading layers
Near-complete absence of fibroblast nuclei
Necrobiosis lipoidica – overview





