Lipodermatosclerosis


LEGEND
Chronic inflammation with perivascular lymphocytic infiltrate in the dermis and presence of siderophages (i.e., macrophages that have phagocytosed hemosiderin)
Lipodermatosclerosis


LEGEND
Dermal findings of stasis dermatitis with extensive neovascularization
Lipodermatosclerosis


LEGEND
Scar remodeling at the level of the hypodermis. This corresponds to a lobular and mixed panniculitis.
Sclerosis of the lobular septa
Lipodermatosclerosis – high magnification

Presence of foamy macrophages around a cavity representing steatonecrosis (fat necrosis)
Lipodermatosclerosis – high magnification


LEGEND
Lipomembranous changes may occasionally be observed (i.e., an eosinophilic papillary configuration projecting into the cavity).
Lipodermatosclerosis


LEGEND
Chronic inflammation with perivascular lymphocytic infiltrate in the dermis
Neovascularization
Lipomembranous changes
Lipodermatosclerosis

Prussian blue stain highlights hemosiderin within macrophages.



