Lipodermatosclerosis

LEGEND

  • Chronic inflammation with perivascular lymphocytic infiltrate in the dermis and presence of siderophages (i.e., macrophages that have phagocytosed hemosiderin)

Lipodermatosclerosis

LEGEND

  • Dermal findings of stasis dermatitis with extensive neovascularization

Lipodermatosclerosis

LEGEND

Scar remodeling at the level of the hypodermis. This corresponds to a lobular and mixed panniculitis.

  • Sclerosis of the lobular septa

Lipodermatosclerosis – high magnification

Presence of foamy macrophages around a cavity representing steatonecrosis (fat necrosis)

Lipodermatosclerosis – high magnification

LEGEND

  • Lipomembranous changes may occasionally be observed (i.e., an eosinophilic papillary configuration projecting into the cavity).

Lipodermatosclerosis

LEGEND

  • Chronic inflammation with perivascular lymphocytic infiltrate in the dermis

  • Neovascularization

  • Lipomembranous changes

Lipodermatosclerosis – high magnification

LEGEND

  • Lipomembranous changes

Lipodermatosclerosis

Prussian blue stain highlights hemosiderin within macrophages.