Interstitial granuloma annulare – low magnification

LEGEND

Presence of mucin, in a smaller amount than in the classic form.

Perivascular lymphoplasmacytic infiltrate.

Normal epidermis.

  • In the interstitial form, a dermal infiltrate of histiocytes is observed between collagen fibers. This can be subtle in early stages.

Interstitial granuloma annulare – low magnification

LEGEND

Minimal and poorly defined necrobiosis compared to the classic form

  • Dermal infiltrate of histiocytes between collagen fibers

Interstitial granuloma annulare

CD68 positive, confirming the presence of histiocytes

Interstitial granuloma annulare

LEGEND

Another classic example

Mild mucin and minimal necrobiosis

Perivascular lymphoplasmacytic infiltrate

  • Dermal infiltrate of histiocytes between collagen fibers