Granuloma annulare – low magnification
Palisading granulomas, meaning granulomas with elongated cells arranged in fence-like formations.
Granulomas are composed of histiocytes and multinucleated giant cells.
Dermal localization, although smaller and more superficial compared to those seen in necrobiosis lipoidica or rheumatoid nodules.
Perivascular lymphohistiocytic infiltrate.
Presence of necrobiosis, though less abundant than that seen in necrobiosis lipoidica or rheumatoid nodules.
Presence of mucin.
Granuloma annulare
LEGEND
Mucin: Loose substance between collagen fibers, appearing pale blue to grayish in color.
Palisading granuloma
Granuloma annulare
LEGEND
Multinucleated giant cells
Palisade
Necrobiosis: Degeneration of collagen fibers, loss of structural integrity, and even presence of cellular debris.
