Cylindroma – low magnification
Adnexal tumor with eccrine differentiation
Dermal tumor without connection to the epidermis
Basaloid cells grouped into irregular nests that fit together like puzzle pieces, separated by a hyaline (pink-staining) basement membrane
Cylindroma
Basaloid cells grouped into irregular nests that fit together like puzzle pieces and are separated by a hyaline basement membrane
Cylindroma
Basaloid cells grouped into irregular nests that fit together like puzzle pieces, separated by a hyaline basement membrane
Cylindroma
LEGEND
Presence of a well-defined eosinophilic hyaline basement membrane at the periphery of each nest
Cylindroma
LEGEND
Nests are composed of 2 types of basaloid cells:
1 – Center: large clear cells with more cytoplasm and pale nuclei
2 – Periphery: small cells with scant cytoplasm arranged in a palisading pattern with hyperchromatic nuclei
Cylindroma
LEGEND
Nests are organized around sweat ducts, with visible ductal lumina within the nests
