Facial granuloma
LEGEND
Contrary to what the name suggests, this is not a granuloma; rather, it is classified among vasculitic and eosinophilic disorders
Epidermis spared
Histopathological features of leukocytoclastic vasculitis may theoretically be present, but they can be very subtle or even absent, as in the presented case
Marked and characteristic Grenz zone
Dense, mixed inflammatory infiltrate in the dermis composed of lymphocytes, histiocytes, neutrophils, plasma cells, and eosinophils
Facial granuloma
LEGEND
Characteristic Grenz zone (band of spared papillary dermis separating the epidermis from the underlying dense dermal infiltrate)
Marked solar elastosis (degenerated bluish material located in the papillary dermis)
Dense, mixed inflammatory infiltrate located beneath the Grenz zone
Facial granuloma
Marked solar elastosis – high magnification (degenerated bluish material located in the papillary dermis)
This finding suggests a photo-exposed location in an adult, with the face being the primary site of occurrence for facial granuloma
Facial granuloma
LEGEND
Dense, mixed inflammatory infiltrate
Plasmocytes
Lymphocytes
Eosinophils
Facial granuloma
LEGEND
Dense, mixed inflammatory infiltrate
Neutrophils (polymorphonuclear cells)
Plasmocytes (eccentric nucleus)
Eosinophils (pink-staining, granular cytoplasm)
