Table of Contents
Darier
LEGEND
Dyskeratosis: apoptotic keratinocytes
Round bodies
Grainy bodies
Darier – low magnification
LEGEND
Suprabasal acantholysis with the presence of dyskeratosis in the form of round bodies and grain bodies
- Papillomatosis
- Hyperkeratosis
- Parakeratosis
Darier
LEGEND
Acantholysis with the presence of clefts
Dyskeratosis characterized by necrotic keratinocytes and premature keratinization in the spinous layer
Darier
LEGEND
Suprabasal acantholysis
- When a vesicle is created by acantholysis, the intercellular bridges are lost (versus the phenomenon of spongiosis), and the detached solitary cells take on a rounded shape.
- Unlike Grover’s disease, the acantholysis in Darier disease is more extensive
Hyperkeratosis
Papillomatosis and acanthosis
